Monday, March 1, 2010

GIGANTINE

Does anyone have information regarding the pharmacology of Gigantine, perhaps even an etymological note? Gigantine is the best sounding substance since the octopus derived Octopamine and the (not yet realized) Hamphetamine sulfate (76:24 ratio of d:l isomers (of course)). I understand Gigantine is basically an isoquinoline which makes activity very unlikely and shulgin only tested the 2,3,4 substitution pattern PEAs in TMA-3 which was found to be inactive at 100mg, not to mention the tertiary amine which will doubtlessly interfere with binding. So i would not hold high hopes for Gigantine...but then again who really Knows?

3 comments:

Joe said...

http://pubs.acs.org/doi/abs/10.1021/jo00976a034

Same substance? From the cactus Carnegiea gigantea, hence the name. The *other* major alkaloid in the cactus is called carnegine (go figure).

Hamilton Morris said...

ah yes thank you, right again, indeed its from Carnegiea gigantea (the Saguaro).

"While the cactus has been reported to treat rheumatism, it is not known to be used hallucinogenically. Yet, it does contain many psychoactive alkaloids such as: 3-methoxytyramine, 3,4-dimethoxyphenethylamine, 3,4 dimethoxy-5-hydroxyphenethylamine, 3,5 dimethoxy-4-hydroxyphenethylamine, Arizonine, Dopamine, Heliamine, Heliamine, dehydro Mescaline, Tyramine, Carnegine, Gigantine (5-hydroxycarnegine), Salsolidine Norcarnegine), Salsolidine, dehydro (Ott 1993)."

Dead Soda said...

i've done my own san pedro alkaloid extraction at home, and have in my possesion a saguaro cactus (Carnegiea gigantea) and was wondering why they aren't used for hallucinogenic experience?? I suppose I could do my own research...but I'm on youtube laughing at 'drive by insults' hahaha. And you're the expert etc...